Research

We do Radical Ring Opening Polymerisation and Hydrogels
… and of course some self-assembly!

The following pages comprises our research

Our group is based the Leibniz-Institute for Polymer Research Dresden (IPF). Information about the people behind the research can be found on the team page. Publications and stats are on google scholar for Dr. Jens Gaitzsch and also comprised in the list of publications, including direct links to the papers. If you need a copy of the paper, please feel free to contact us.

Radical Ring-Opening Polymerisation

Synthesising a polyester from a radical polymerisation has some interesting features compared to a classic ring-opening polymerisation. The radical feature now allows for functional groups like amines. Since the final structure is still a polyester, it can by hydrolysed and can also be biodegraded using esterase. Altogether, this polymerisation does hold some very compelling features but also some tough challanges which we will conquer along the way.

Latest publication: DOI: 10.10.1016/j.eurpolymj.2020.109851

Responsive Hydrogels

It is somewhat of an age-old question of polymer chemstry: How can we apply the vast array of polymers with all their functionalities for a certain application. Within the RTG “Hydrogel-Based Microsystems” with the TU Dresden, we apply this onto hydrogels and their use in microfluidics. Our hydrogels tend to hold responsive units (e.g. from complexation) as responsive additional cross-linking points.

Latest publication: 10.1039/D0SM00833H

Self-Assembly

It is fair to say that we have a bit of a history in the field. Amphiphilic block-copolymers can self-assembly into a large array of structures, but we find the polymersomes most compelling. With their aqueous core and hydrophobic part of the membrane, they can host hydrophilic and hydrophobic cargo. If a molecule contains both domains, like protein, it can even host these ones in their membrane. A lot has been seen and done on these vesicles, but as they say: There is loads of room at the bottom!

Our reviews in the field cover polymersomes in general, but also ABC triblock-copolymers and cross-linked polymersomes specifically.

Latest publication: 10.1039/D0RA04274A

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